Camsap2 Gene Summary [Rat]
Predicted to enable microtubule minus-end binding activity. Involved in axon development and regulation of dendrite development. Predicted to be located in Golgi apparatus; cytosol; and microtubule cytoskeleton. Predicted to colocalize with microtubule minus-end. Orthologous to human CAMSAP2 (calmodulin regulated spectrin associated protein family member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Camsap2 |
| Official Name | calmodulin regulated spectrin-associated protein family, member 2 [Source:RGD Symbol;Acc:1310950] |
| Ensembl ID | ENSRNOG00000008741 |
| Bio databases IDs | |
| Aliases | calmodulin regulated spectrin-associated protein family, member 2 |
| Synonyms | 1600013L13Rik, 4930541M15Rik, calmodulin regulated spectrin associated protein family member 2, calmodulin regulated spectrin-associated protein family, member 2, CAMSAP1L1, mKIAA1078, RGD1310950 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Camsap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- Spectrin-binding region of Ca2+-Calmodulin
- calponin homology (CH) domain superfamily
- Microtubule-binding calmodulin-regulated spectrin-associated
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- growth failure
- colorectal cancer
- organismal death
- insulin-dependent diabetes mellitus
- epilepsy
- metastasis
- myocardial infarction
role in cell
- expression in
- migration
- growth
- phosphorylation in
- abnormal morphology
- organization
- development
- invasion by
- polymerization
- growth in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular tracklike structure
- microtubule cytoskeleton
- basal bodies
- centrosome
- Golgi Apparatus
- cytosol
- axons
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Camsap2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of dendrite development
- regulation of organelle organization
- regulation of microtubule polymerization
- negative regulation of microtubule depolymerization
- microtubule cytoskeleton organization
- cytoplasmic microtubule organization
Cellular Component
Where in the cell the gene product is active
- centrosome
- cilium basal body
- cytosol
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- protein binding
- spectrin binding
- microtubule minus-end binding