Mpdu1 Gene Summary [Rat]
Predicted to be involved in oligosaccharide biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation If. Orthologous to human MPDU1 (mannose-P-dolichol utilization defect 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mpdu1 |
| Official Name | mannose-P-dolichol utilization defect 1 [Source:RGD Symbol;Acc:1307699] |
| Ensembl ID | ENSRNOG00000012162 |
| Bio databases IDs | |
| Aliases | mannose-P-dolichol utilization defect 1 |
| Synonyms | CDGIF, HBEBP2BPA, LEC35, mannose-P-dolichol utilization defect 1, My008, PP3958, PQLC5, SL15, SLC66A5, Supl15h |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mpdu1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sugar efflux transporter for intercellular exchange
- protein binding
- PQ loop repeat
- Lysosomal Cystine Transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mpdu1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oligosaccharide biosynthetic process
- protein folding
- dolichol-linked oligosaccharide biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding