Cmas Gene Summary [Rat]

Predicted to enable N-acylneuraminate cytidylyltransferase activity. Predicted to be involved in CMP-N-acetylneuraminate biosynthetic process; N-acetylneuraminate metabolic process; and glycosylation. Predicted to be active in nucleoplasm. Orthologous to human CMAS (cytidine monophosphate N-acetylneuraminic acid synthetase). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Cmas
Official Name
cytidine monophosphate N-acetylneuraminic acid synthetase [Source:RGD Symbol;Acc:1310911]
Ensembl ID
ENSRNOG00000013816
Bio databases IDs NCBI: 312826 Ensembl: ENSRNOG00000013816
Aliases cytidine monophosphate N-acetylneuraminic acid synthetase
Synonyms CMPNeu5Ac, CSS, cytidine monophosphate N-acetylneuraminic acid synthetase, cytidine monophospho-N-acetylneuraminic acid synthetase, D6Bwg0250e
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cmas often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
  • N-acylneuraminate cytidylyltransferase
  • Cytidylyltransferase
  • acylneuraminate cytidylyltransferase
  • enzyme
  • glycosyltransferase family A
  • Haloacid Dehalogenase-like Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • metastasis
  • infection by Enterovirus D68
regulated by
regulates
role in cell
  • expression in
  • number
  • phagocytosis by
  • production in
  • sialylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cmas gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • N-acetylneuraminate metabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • N-acylneuraminate cytidylyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.