YIPF5 Gene Summary [Human]
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; regulation of ER to Golgi vesicle-mediated transport; and vesicle fusion with Golgi apparatus. Located in Golgi apparatus; endoplasmic reticulum; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | YIPF5 |
| Official Name | Yip1 domain family member 5 [Source:HGNC Symbol;Acc:HGNC:24877] |
| Ensembl ID | ENSG00000145817 |
| Bio databases IDs | |
| Aliases | Yip1 domain family member 5 |
| Synonyms | 2610311I19Rik, Ac2-256, FinGER5, MEDS2, SB140, SMAP-5, YIP1A, Yip1 domain family member 5, Yip1 domain family, member 5, YIPFalpha1A |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human YIPF5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N-terminal tail
- Yip1 domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- microcephaly, epilepsy, and diabetes syndrome type 2
- refractive error
regulates
- HTR1A
- insulin
- Vsvg
role in cell
- organization
- dispersal
- dispersal in
- stacking in
- stacking
- restructuring in
- restructuring
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- endomembrane system
- Golgi Apparatus
- Endoplasmic Reticulum
- granules
- nucleoplasm
- peri-Golgi vesicles
- transport vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human YIPF5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ER to Golgi vesicle-mediated transport
- insulin processing
- regulation of ER to Golgi vesicle-mediated transport
- protein transport
- vesicle fusion with Golgi apparatus
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- trans-Golgi network
- intracellular membrane-bounded organelle
- Golgi apparatus
- endoplasmic reticulum
- endoplasmic reticulum exit site
- ER to Golgi transport vesicle
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding