Scara3 Gene Summary [Rat]
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to be located in endoplasmic reticulum. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human SCARA3 (scavenger receptor class A member 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Scara3 |
| Official Name | scavenger receptor class A, member 3 [Source:RGD Symbol;Acc:1309269] |
| Ensembl ID | ENSRNOG00000016177 |
| Bio databases IDs | |
| Aliases | scavenger receptor class A, member 3 |
| Synonyms | APC7, C130058N24RIK, CSR, CSR1, MSLR1, MSRL1, scavenger receptor class A member 3, scavenger receptor class A, member 3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Scara3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- scavenger receptor
- Collagen triple helix repeat (20 copies)
- protein binding
- transmembrane receptor
Pathways
Biological processes and signaling networks where the Scara3 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Golgi Apparatus
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Scara3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to oxidative stress
- vesicle-mediated transport
- UV protection
- toll-like receptor 3 signaling pathway
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- collagen
- endoplasmic reticulum
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- scavenger receptor activity