Lactb Gene Summary [Rat]

Enables identical protein binding activity. Predicted to be involved in proteolysis and regulation of lipid metabolic process. Predicted to be located in cytosol. Predicted to be active in mitochondrion. Orthologous to human LACTB (lactamase beta). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lactb
Official Name
lactamase, beta [Source:RGD Symbol;Acc:1304788]
Ensembl ID
ENSRNOG00000018081
Bio databases IDs NCBI: 300803 Ensembl: ENSRNOG00000018081
Aliases lactamase, beta
Synonyms G24, LACT-1, lactamase beta, lactamase, beta, lactamase β, lactamase, β, MRPL56, β Lactamase
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lactb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Penicillin binding protein transpeptidase domain
  • beta-lactamase
  • peptidase
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • age-related macular degeneration
  • prostate cancer
  • mucinous ovarian carcinoma
  • mucinous ovarian cancer
  • gastric cancer
  • serous ovarian adenocarcinoma
  • serous ovarian cancer
  • ovarian neoplasia
  • obesity
regulated by
  • Bacillus anthracis strain Sterne
  • SRP72
  • IL4
  • OXCT1
  • TFAP2A
  • STAT6
  • Dengue virus 2 Thailand/NGS-C/1944
regulates
role in cell
  • expression in
  • growth
  • proliferation
  • differentiation
  • autophagy in
  • formation by
  • epithelial-mesenchymal transition

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • cytosol
  • microsome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Lactb gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis
  • lipid metabolic process
  • regulation of lipid metabolic process

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • peptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.