Cdc42ep2 Gene Summary [Rat]
Predicted to enable GTPase activator activity; opioid peptide activity; and small GTPase binding activity. Predicted to be involved in several processes, including Rho protein signal transduction; positive regulation of cellular component biogenesis; and regulation of cell shape. Predicted to act upstream of or within cellular response to type II interferon. Predicted to be located in several cellular components, including cytosol; microtubule cytoskeleton; and phagocytic vesicle. Predicted to be active in cytoplasm; cytoskeleton; and plasma membrane. Orthologous to human CDC42EP2 (CDC42 effector protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cdc42ep2 |
| Official Name | CDC42 effector protein 2 [Source:RGD Symbol;Acc:1310253] |
| Ensembl ID | ENSRNOG00000020904 |
| Bio databases IDs | |
| Aliases | CDC42 effector protein 2 |
| Synonyms | 1110008C05Rik, BORG1, CDC42 effector protein 2, CEP2, D19Bwg1013e |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cdc42ep2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cdc42 effector
- CRIB
- enzyme binding
- GTPase activator
- protein binding
- opioid peptide
Pathways
Biological processes and signaling networks where the Cdc42ep2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- microtubule cytoskeleton
- Cytoplasm
- cellular membrane
- cytosol
- filopodia
- phagosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cdc42ep2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell shape
- positive regulation of pseudopodium assembly
- positive regulation of actin filament polymerization
- actin filament organization
- cellular response to interferon-gamma
- Rho protein signal transduction
- actin cytoskeleton organization
- positive regulation of protein complex assembly
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- cytoskeleton
- cytoplasm
- membrane
- phagocytic vesicle
- cytosol
- endomembrane system
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- opioid peptide activity
- GTPase activator activity
- small GTPase binding