AABR07013464.1 Gene Summary [Rat]

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in synapse. Predicted to be active in cytoplasm. Orthologous to human ARHGEF38 (Rho guanine nucleotide exchange factor 38). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
AABR07013464.1
Official Name
Rho guanine nucleotide exchange factor 38 [Source:NCBI gene;Acc:295449]
Ensembl ID
ENSRNOG00000023965
Bio databases IDs NCBI: 295449 Ensembl: ENSRNOG00000023965
Aliases Rho guanine nucleotide exchange factor 38
Synonyms 9130221D24Rik, D630013G24Rik, FLJ43963, LOC102556447, RGD1311728, Rho guanine nucleotide exchange factor 38
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Aabr07013464.1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RhoGEF
  • protein binding
  • BAR domain
  • Bin/Amphiphysin/Rvs domain
  • RhoGEF domain
  • Src Homology 3 domain superfamily

Pathways

Biological processes and signaling networks where the Aabr07013464.1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • idiopathic scoliosis
  • chronic obstructive pulmonary disease
  • estrogen receptor positive breast cancer
  • breast cancer
regulated by
  • THZ531

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Aabr07013464.1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • guanyl-nucleotide exchange factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.