Kcnn1 Gene Summary [Rat]
Enables small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Located in neuronal cell body. Orthologous to human KCNN1 (potassium calcium-activated channel subfamily N member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kcnn1 |
| Official Name | potassium calcium-activated channel subfamily N member 1 [Source:RGD Symbol;Acc:2962] |
| Ensembl ID | ENSRNOG00000029264 |
| Bio databases IDs | |
| Aliases | potassium calcium-activated channel subfamily N member 1 |
| Synonyms | AC019302.1, Gm3624, hSK1, KCa2.1, LOC100360811, potassium calcium-activated channel subfamily N member 1, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1, SK1, SKCA1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kcnn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calcium-activated SK potassium channel
- inward rectifier potassium channel
- binding protein
- calmodulin binding
- small conductance calcium-activated potassium channel
- calmodulin binding domain
- calcium-activated potassium channel
- alpha helix
- ion channel
- HR1
Pathways
Biological processes and signaling networks where the Kcnn1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cellular membrane
- synaptic vesicles
- perikaryon
- mossy fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Kcnn1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transport
- potassium ion transmembrane transport
- synaptic transmission
Cellular Component
Where in the cell the gene product is active
- voltage-gated potassium channel complex
- synapse
- neuronal cell body
- neuron projection
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- calcium-activated potassium channel activity
- calmodulin binding
- inward rectifier potassium channel activity
- small conductance calcium-activated potassium channel activity