Mt1 Gene Summary [Rat]
Predicted to be involved in cellular response to cadmium ion and cellular response to zinc ion. Predicted to be located in cytoplasm and nucleus. Orthologous to human MT1E (metallothionein 1E). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mt1 |
| Official Name | metallothionein 1 [Source:RGD Symbol;Acc:3117] |
| Ensembl ID | ENSRNOG00000038047 |
| Bio databases IDs | |
| Aliases | metallothionein 1 |
| Synonyms | METALLOTHIONEIN 1, Metallothionein2, Mt, Mt1a, MT1B, Mt2, MT-I |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- copper ion binding
- metallothionein beta domain
- zinc ion binding
- metallothionein alpha domain
- Metallothionein
- metal ion binding
Pathways
Biological processes and signaling networks where the Mt1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial neoplasia
- neoplasia
- abdominal cancer
- cancer
- epithelial cancer
- neuropathy
- tubulo-interstitial fibrosis
- hyperplasia
- hepatic fibrosis
- clonic seizure
role in cell
- expression in
- formation
- growth
- number
- cell death
- proliferation
- apoptosis
- cell viability
- function
- survival
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- lysosome
- Mitochondria
- cytosol
- mitochondrial intermembrane space