STYK1 Gene Summary [Human]
Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | STYK1 |
| Official Name | serine/threonine/tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:18889] |
| Ensembl ID | ENSG00000060140 |
| Bio databases IDs | |
| Aliases | serine/threonine/tyrosine kinase 1 |
| Synonyms | 9130025L13, NOK, RGD1564211, serine/threonine/tyrosine kinase 1, SuRTK106 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STYK1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- Kinase-like
- protein binding
- Protein kinase domain
- protein-tyrosine kinase
- Tyrosine kinase, catalytic domain
Pathways
Biological processes and signaling networks where the STYK1 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Parkinson disease
role in cell
- phosphorylation in
- development
- transformation
- cell viability
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STYK1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein phosphorylation
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein tyrosine kinase activity
- protein binding
- non-membrane spanning protein tyrosine kinase activity