NDRG3 Gene Summary [Human]
Predicted to be involved in signal transduction. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NDRG3 |
| Official Name | NDRG family member 3 [Source:HGNC Symbol;Acc:HGNC:14462] |
| Ensembl ID | ENSG00000101079 |
| Bio databases IDs | |
| Aliases | NDRG family member 3 |
| Synonyms | 4833415O14Rik, LOC100366265, LOC108348290, NDR3, NDRG family member 3, N-myc downstream regulated gene 3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NDRG3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alpha/beta hydrolase fold
- alpha/beta hydrolases
- Ndr family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Huntington disease
- melanoma
- melanoma cancer
- non-melanoma skin cancer
role in cell
- expression in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell cortex
- synaptic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NDRG3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- negative regulation of cell growth
- spermatogenesis
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm