CCNY Gene Summary [Human]
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009]
Details
| Type | Protein Coding |
| Official Symbol | CCNY |
| Official Name | cyclin Y [Source:HGNC Symbol;Acc:HGNC:23354] |
| Ensembl ID | ENSG00000108100 |
| Bio databases IDs | |
| Aliases | cyclin Y |
| Synonyms | 1700025H17Rik, 3110050L10Rik, 4631402G10Rik, 5730405I09Rik, C10orf9, CBCP1, CCNX, CFP1, cyclin Y, RGD1565969 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CCNY often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cyclin box fold superfamily
- Cyclin, N-terminal domain
- protein binding
- domain present in cyclins, TFIIB and Retinoblastoma
- cyclin-dependent protein kinase regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- eosinophilic esophagitis
- inflammatory bowel disease
- hyperactive behavior
- ulcerative colitis
- aortic valve calcification
- prostate cancer
- preeclampsia
regulates
- CDK16
- carbon dioxide
- cholesterol
- triacylglycerol
- oxygen
- fatty acid
role in cell
- activation in
- differentiation
- autophagy by
- size
- G2/M phase transition
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CCNY gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- positive regulation of autophagy
- positive regulation of cyclin-dependent protein kinase activity
- regulation of protein kinase activity
- G2/M transition of mitotic cell cycle
- regulation of canonical Wnt receptor signaling pathway
- spermatogenesis
- Wnt receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasmic cyclin-dependent protein kinase holoenzyme complex
- cyclin-dependent protein kinase holoenzyme complex
- nucleolus
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- cyclin-dependent protein kinase regulator activity
- protein binding