NT5C1A Gene Summary [Human]
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | NT5C1A |
| Official Name | 5'-nucleotidase, cytosolic IA [Source:HGNC Symbol;Acc:HGNC:17819] |
| Ensembl ID | ENSG00000116981 |
| Bio databases IDs | |
| Aliases | 5'-nucleotidase, cytosolic IA, cytosolic 5' nucleotidase, type 1A, AMP-specific 5'-NT, cytosolic 5'-nucleotidase IA |
| Synonyms | 5'-nucleotidase, cytosolic IA, CN1, CN1A, CN-I, CN-IA, Gm49 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NT5C1A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 5'-nucleotidase
- phosphatase
- protein binding
- magnesium ion binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NT5C1A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- adenosine metabolic process
- AMP catabolic process
- dGMP catabolic process
- nucleoside metabolic process
- dAMP catabolic process
- IMP catabolic process
- allantoin metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- nucleotide binding
- magnesium ion binding
- protein binding
- 5'-nucleotidase activity
- IMP 5'-nucleotidase activity