CTNNAL1 Gene Summary [Human]
Predicted to enable actin filament binding activity and cadherin binding activity. Acts upstream of or within Rho protein signal transduction. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CTNNAL1 |
| Official Name | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] |
| Ensembl ID | ENSG00000119326 |
| Bio databases IDs | |
| Aliases | catenin alpha like 1, alpha-catulin, alpha2-catulin |
| Synonyms | ACRP, AI616177, alpha CATENIN LIKE, alpha-CATU, alpha CATULIN, C86009, catenin alpha-like 1, catenin α-like 1, CATNAL1, CLLP, Ctnnal1 predicted, α CATENIN LIKE, α-CATU, α CATULIN |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CTNNAL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Vinculin family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- serous ovarian adenocarcinoma
- serous ovarian cancer
- renal cell carcinoma
- renal cell cancer
role in cell
- production in
- expression in
- activation in
- migration
- invasiveness
- signaling in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CTNNAL1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell adhesion
- Rho protein signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- actin filament binding
- protein binding
- cadherin binding