UBAP2 Gene Summary [Human]
The protein encoded by this gene contains a UBA (ubiquitin associated) domain, which is characteristic of proteins that function in the ubiquitination pathway. This gene may show increased expression in the adrenal gland and lymphatic tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Details
| Type | Protein Coding |
| Official Symbol | UBAP2 |
| Official Name | ubiquitin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:14185] |
| Ensembl ID | ENSG00000137073 |
| Bio databases IDs | |
| Aliases | ubiquitin associated protein 2 |
| Synonyms | 1190005K07Rik, mKIAA1491, ubiquitin-associated protein 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UBAP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UBA domain-like superfamily
- Ubiquitin-associated protein 2
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- non-insulin-dependent diabetes mellitus
- epithelial cancer
- prostate cancer
- prostatic carcinoma
- colorectal cancer
- luminal breast cancer
- organismal death
- osteoporosis
- Parkinson disease
role in cell
- expression in
- migration
- proliferation
- apoptosis
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic mRNA processing body
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human UBAP2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of gene expression
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytoplasmic mRNA processing body
- chromosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- cadherin binding