UTP11 Gene Summary [Human]

Enables RNA binding activity. Involved in nervous system development and positive regulation of apoptotic process. Located in cytoplasm; extracellular space; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
UTP11
Official Name
UTP11 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24329]
Ensembl ID
ENSG00000183520
Bio databases IDs NCBI: 51118 Ensembl: ENSG00000183520
Aliases UTP11 small subunit processome component
Synonyms 2700082D03Rik, CGI-94, LOC51118, RGD1559610, UTP11L, UTP11 small subunit processome component, UTP11, small subunit processome component
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UTP11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Utp11 protein
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • breast cancer
  • liver cancer
  • epithelial cancer
  • organismal death
  • colorectal cancer
  • hepatocellular carcinoma
  • immunodeficiency
  • infection by vesicular stomatitis virus
regulated by
regulates
role in cell
  • ferroptosis
  • cell viability
  • expression in
  • growth
  • apoptosis
  • processing in
  • ubiquitination in
  • synthesis in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • pre-ribosome
  • Cytoplasm
  • Extracellular Space
  • cytosol
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human UTP11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal small subunit biogenesis
  • positive regulation of apoptotic process
  • nervous system development
  • rRNA processing

Cellular Component

Where in the cell the gene product is active
  • small-subunit processome
  • extracellular space
  • cytoplasm
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

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