CCDC137 Gene Summary [Human]

Enables RNA binding activity. Located in chromosome and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
CCDC137
Official Name
coiled-coil domain containing 137 [Source:HGNC Symbol;Acc:HGNC:33451]
Ensembl ID
ENSG00000185298
Bio databases IDs NCBI: 339230 Ensembl: ENSG00000185298
Aliases coiled-coil domain containing 137
Synonyms 3110023B02Rik, coiled-coil domain containing 137, RaRF, SIMILAR TO RIKEN CDNA 3110023B02
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CCDC137 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • tumorigenesis
  • organismal death
  • liver cancer
  • hepatocellular carcinoma
regulated by
role in cell
  • proliferation
  • invasion by
  • upregulation in
  • migration
  • colony formation by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • fibrillar center
  • chromosome
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CCDC137 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • chromosome
  • nucleolus
  • fibrillar center

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.