Tpd52l2 Gene Summary [Mouse]

Predicted to enable protein homodimerization activity. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human TPD52L2 (TPD52 like 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Tpd52l2
Official Name
tumor protein D52-like 2 [Source:MGI Symbol;Acc:MGI:1913564]
Ensembl ID
ENSMUSG00000000827
Bio databases IDs NCBI: 66314 Ensembl: ENSMUSG00000000827
Aliases tumor protein D52-like 2
Synonyms 2810411G23RIK, D54, TPD52 like 2, TPD54, tumor protein D52-like 2, tumour protein D52-like 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tpd52l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Tumour protein D52 family
  • protein homodimerization
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
regulated by
  • TNF
  • IL4
  • Rpmi 8226 cells
  • PML
  • FN1
  • DAP3
  • IL1B
  • mir-122 (includes others)
  • isobutylmethylxanthine
  • Jurkat E6.1 cells
regulates
role in cell
  • migration
  • invasion by
  • proliferation
  • dispersal
  • dispersal in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • pH resistant lipid raft fraction
  • perinuclear region
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tpd52l2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • carbohydrate metabolic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.