Ly9 Gene Summary [Mouse]
Predicted to be involved in T-helper 17 cell lineage commitment and positive regulation of interleukin-17 production. Located in cell surface. Orthologous to human LY9 (lymphocyte antigen 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ly9 |
| Official Name | lymphocyte antigen 9 [Source:MGI Symbol;Acc:MGI:96885] |
| Ensembl ID | ENSMUSG00000004707 |
| Bio databases IDs | |
| Aliases | lymphocyte antigen 9 |
| Synonyms | CD229, hly9, Lgp100, lymphocyte antigen 9, mLY9, SLAMF3, T100 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ly9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- cytoplasmic domain
- immunoglobulin domain
- cytosolic tail domain
- Immunoglobulin V-set domain
- tyrosine-based motif
- Grb2 binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- systemic lupus erythematosus
- multisystem inflammatory syndrome in children
- diabetic nephropathy
- tauopathy
- amyloidosis
role in cell
- expression in
- proliferation
- production in
- quantity
- survival
- killing
- elimination
- expansion
- number
- lysis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ly9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
- T-helper 17 cell lineage commitment
- positive regulation of interleukin-17 production
- T cell activation
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- external side of plasma membrane
- plasma membrane