Cox6c Gene Summary [Mouse]
Predicted to be involved in oxidative phosphorylation. Located in mitochondrion. Part of respiratory chain complex IV. Is active in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human COX6C (cytochrome c oxidase subunit 6C). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Cox6c |
| Official Name | cytochrome c oxidase subunit 6C [Source:MGI Symbol;Acc:MGI:104614] |
| Ensembl ID | ENSMUSG00000014313 |
| Bio databases IDs | |
| Aliases | cytochrome c oxidase subunit 6C |
| Synonyms | COVIc, Cox6c2, COX-VIc, cytochrome c oxidase subunit 6C, Cytochrome C Oxidase Subunit Vic |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cox6c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytochrome-c oxidase
- enzyme
- protein binding
- Cytochrome c oxidase subunit VIc
- Cytochrome c oxidase subunit VIc-like
Pathways
Biological processes and signaling networks where the Cox6c gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metabolic syndrome X
- chronic kidney disease
- Huntington disease
- chronic obstructive pulmonary disease
- bipolar disorder
- chromophobe renal cell carcinoma
- chromophobe renal cancer
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- myofilaments
- mitochondrial membrane
- mitochondrial intermembrane space
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cox6c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- generation of precursor metabolites and energy
- mitochondrial electron transport, cytochrome c to oxygen
- cellular respiration
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
- mitochondrion
- mitochondrial respiratory chain complex IV
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding