Ckmt2 Gene Summary [Mouse]
Predicted to enable cardiolipin binding activity and creatine kinase activity. Predicted to be involved in phosphocreatine biosynthetic process. Predicted to act upstream of or within phosphocreatine metabolic process. Located in mitochondrion. Is expressed in several structures, including gut; heart; lung; skeletal muscle; and thymus. Orthologous to human CKMT2 (creatine kinase, mitochondrial 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ckmt2 |
| Official Name | creatine kinase, mitochondrial 2 [Source:MGI Symbol;Acc:MGI:1923972] |
| Ensembl ID | ENSMUSG00000021622 |
| Bio databases IDs | |
| Aliases | creatine kinase, mitochondrial 2 |
| Synonyms | 2300008A19Rik, creatine kinase, mitochondrial 2, KCRS, mib-CK, ScCKmit, sMiCK, S-MtCK |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ckmt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- phospholipid binding
- binding protein
- Phosphagen (guanidino) kinases
- creatine kinase
- ATP:guanido phosphotransferase, N-terminal domain
- protein binding
- ATP:guanido phosphotransferase, C-terminal catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Mitochondria
- mitochondrial membrane
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ckmt2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- muscle contraction
- phosphocreatine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- creatine kinase activity