Trip10 Gene Summary [Rat]
Predicted to enable identical protein binding activity. Involved in several processes, including negative regulation of cardiac muscle cell apoptotic process; positive regulation of cell growth involved in cardiac muscle cell development; and response to food. Predicted to be located in nucleoplasm. Orthologous to human TRIP10 (thyroid hormone receptor interactor 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Trip10 |
| Official Name | thyroid hormone receptor interactor 10 [Source:RGD Symbol;Acc:621145] |
| Ensembl ID | ENSRNOG00000055524 |
| Bio databases IDs | |
| Aliases | thyroid hormone receptor interactor 10 |
| Synonyms | CIP4, Cip4/2, HSTP, STOT, STP, thyroid hormone receptor interactor 10 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Trip10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTPase binding domain
- microtubule binding domain
- Fes/CIP4, and EFC/F-BAR homology domain
- protein binding
- Bin/Amphiphysin/Rvs domain
- identical protein binding
- HR1
- Src Homology 3 domain superfamily
Pathways
Biological processes and signaling networks where the Trip10 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- delayed hypersensitive reaction
role in cell
- cell death
- migration
- activation in
- activity
- function
- polarization
- invasion
- assembly
- formation
- crizotinib sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- soluble fraction
- intracellular membrane-bounded organelle
- cell periphery
- cellular membrane
- Nucleus
- microtubules
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Trip10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell communication
- signal transduction
- endocytosis
- actin cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- cell projection
- phagocytic cup
- lysosome
- nucleoplasm
- extracellular vesicular exosome
- cytoskeleton
- perinuclear region of cytoplasm
- cytoplasm
- cell cortex
- intracellular membrane-bounded organelle
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- lipid binding