Prpf40b Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nuclear speck. Predicted to be part of U1 snRNP and U2-type prespliceosome. Orthologous to human PRPF40B (pre-mRNA processing factor 40 homolog B). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prpf40b |
| Official Name | pre-mRNA processing factor 40B [Source:MGI Symbol;Acc:MGI:1925583] |
| Ensembl ID | ENSMUSG00000023007 |
| Bio databases IDs | |
| Aliases | pre-mRNA processing factor 40B |
| Synonyms | 2610317D23Rik, HYPC, LOC103692979, pre-mRNA processing factor 40B, pre-mRNA processing factor 40 homolog B, RGD1565411 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prpf40b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FF domain
- Domain with 2 conserved Trp (W) residues
- Contains two conserved F residues
- WW
- protein binding
- WW domain
Pathways
Biological processes and signaling networks where the Prpf40b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prpf40b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA cis splicing, via spliceosome
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nuclear speck
- U2-type prespliceosome
- U1 snRNP
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding