Cdca3 Gene Summary [Mouse]
Predicted to be involved in cell division and protein ubiquitination. Predicted to be located in adherens junction. Is expressed in several structures, including brain; liver lobe; olfactory epithelium; orbito-sphenoid; and renal cortex. Orthologous to human CDCA3 (cell division cycle associated 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cdca3 |
| Official Name | cell division cycle associated 3 [Source:MGI Symbol;Acc:MGI:1315198] |
| Ensembl ID | ENSMUSG00000023505 |
| Bio databases IDs | |
| Aliases | cell division cycle associated 3 |
| Synonyms | 2410005A12Rik, C8, cell division cycle associated 3, GRCC8, TOME-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cdca3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- refractive error
- myopia
- lung adenocarcinoma
- lung adenocarcinoma formation
- hyperopia
- open-angle glaucoma
- ophthalmic disorder
- astigmatism
- MYC mutation positive B-cell lymphoma
- lymphomagenesis
role in cell
- proliferation
- expression in
- migration
- josamycin sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cdca3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- adherens junction
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding