Cd5 Gene Summary [Mouse]
Acts upstream of or within T cell costimulation and apoptotic signaling pathway. Located in external side of plasma membrane. Is expressed in gut and male reproductive gland or organ. Orthologous to human CD5 (CD5 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd5 |
| Official Name | CD5 antigen [Source:MGI Symbol;Acc:MGI:88340] |
| Ensembl ID | ENSMUSG00000024669 |
| Bio databases IDs | |
| Aliases | CD5 antigen |
| Synonyms | CD5 ANTIGEN, CD5 molecule, LEU1, LOC100911215, Ly-1, Ly-12, Ly-A, Lyt-1, OKT1, T1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Scavenger receptor cysteine-rich domain
- extracellular domain
- cytoplasmic domain
- ectodomain
- transmembrane domain
- signal peptide
- protein binding
- cytosolic tail domain
- transmembrane receptor
- Scavenger receptor Cys-rich
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- Waldenström macroglobulinemia
- liver cancer
- diffuse large B-cell lymphoma
- B-cell non-Hodgkin disease
- mature B-cell neoplasia
- T-cell prolymphocytic leukemia
- hypothyroidism
- polyglandular autoimmune syndrome type 1
- hairy cell leukemia
role in cell
- apoptosis
- phosphorylation in
- binding in
- expression in
- production in
- quantity
- activation in
- proliferation
- number
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
- immunological synapses
- plasma membrane extracellular face
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cd5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- T cell costimulation
- apoptotic signaling pathway
- cell recognition
Cellular Component
Where in the cell the gene product is active
- external side of plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- signaling receptor activity