Fibp Gene Summary [Mouse]
Predicted to enable fibroblast growth factor binding activity. Predicted to be located in membrane and nuclear speck. Predicted to be active in nucleus. Orthologous to human FIBP (FGF1 intracellular binding protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Fibp |
| Official Name | fibroblast growth factor (acidic) intracellular binding protein [Source:MGI Symbol;Acc:MGI:1926233] |
| Ensembl ID | ENSMUSG00000024911 |
| Bio databases IDs | |
| Aliases | fibroblast growth factor (acidic) intracellular binding protein |
| Synonyms | 2010004G08Rik, 2010005N21Rik, 3010027N18Rik, FGF1 intracellular binding protein, FGF (Acidic) Intracellular Binding, FGFIBP, FIBP-1, fibroblast growth factor (acidic) intracellular binding protein, TROFAS |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fibp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- fibroblast growth factor binding
- Acidic fibroblast growth factor binding (FIBP)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- Thauvin-Robinet-Faivre syndrome
- lung adenocarcinoma
- lung adenocarcinoma formation
- organismal death
- diffuse cutaneous systemic sclerosis
- Crohn disease
role in cell
- expression in
- phosphorylation in
- proliferation
- G2/M phase
- growth
- formation
- formation in
- quantity
- aggregation
- radiosensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- intracellular membranes
- cellular membrane
- Mitochondria
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fibp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fibroblast growth factor receptor signaling pathway
- platelet aggregation
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- mitochondrion
- membrane
- endomembrane system
Molecular Function
What the gene product does at the molecular level
- fibroblast growth factor binding