Il1f6 Gene Summary [Mouse]
Enables cytokine activity. Acts upstream of or within positive regulation of interleukin-6 production. Located in extracellular space. Orthologous to human IL36A (interleukin 36 alpha). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Il1f6 |
| Official Name | interleukin 1 family, member 6 [Source:MGI Symbol;Acc:MGI:1859324] |
| Ensembl ID | ENSMUSG00000026984 |
| Bio databases IDs | |
| Aliases | interleukin 1 family, member 6 |
| Synonyms | Fil1, If36a, Il1e, Il1f6, Il1f9, IL-1H1, IL1RP2, interleukin 36A |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Il1f6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- interleukin-1 receptor binding
- cytokine
- beta-trefoil domain found in the interleukin-1 (IL-1) family of cytokines
Pathways
Biological processes and signaling networks where the Il1f6 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space