Rae1

Predicted to enable RNA binding activity and ubiquitin binding activity. Predicted to be involved in RNA export from nucleus; regulation of mitotic spindle organization; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to be located in mitotic spindle pole and nucleus. Predicted to be part of nuclear pore. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human RAE1 (ribonucleic acid export 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rae1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Rae1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rae1 gene, providing context for its role in the cell.