Polr3gl Gene Summary [Mouse]
Enables chromatin binding activity. Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is expressed in alimentary system; eye; and nervous system. Orthologous to human POLR3GL (RNA polymerase III subunit GL). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Polr3gl |
| Official Name | polymerase (RNA) III (DNA directed) polypeptide G like [Source:MGI Symbol;Acc:MGI:1917120] |
| Ensembl ID | ENSMUSG00000028104 |
| Bio databases IDs | |
| Aliases | polymerase (RNA) III (DNA directed) polypeptide G like |
| Synonyms | 2010003I19Rik, flj32422, LOC682744, polymerase (RNA) III (DNA directed) polypeptide G like, RNA polymerase III subunit GL, RPC32 beta, RPC32HOM, RPC32 β, SOFM |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Polr3gl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- chromatin binding
- protein binding
- DNA-directed RNA polymerase III subunit Rpc31
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- short stature, oligodontia, dysmorphic facies and motor delay
- intellectual disability and developmental delay
regulates
- DNA promoter
- DNA endogenous promoter
- RNA polymerase iii
role in cell
- growth
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Polr3gl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription from RNA polymerase III promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- DNA-directed RNA polymerase III complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding