Bcl7c Gene Summary [Mouse]

Predicted to be involved in several processes, including positive regulation of stem cell population maintenance; regulation of cell cycle process; and regulation of nucleobase-containing compound metabolic process. Part of SWI/SNF complex. Is expressed in embryo. Orthologous to human BCL7C (BAF chromatin remodeling complex subunit BCL7C). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Bcl7c
Official Name
B cell CLL/lymphoma 7C [Source:MGI Symbol;Acc:MGI:1332237]
Ensembl ID
ENSMUSG00000030814
Bio databases IDs NCBI: 12055 Ensembl: ENSMUSG00000030814
Aliases B cell CLL/lymphoma 7C
Synonyms BAF chromatin remodeling complex subunit BCL7C, B cell CLL/lymphoma 7C, C230096E12Rik, SMARCJ3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bcl7c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • BCL7, N-terminal conserver region
  • protein binding
  • HTH domain in Mos1 transposase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diffuse cutaneous systemic sclerosis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Bcl7c gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromatin remodeling
  • regulation of mitotic metaphase/anaphase transition
  • negative regulation of cell differentiation
  • apoptotic process
  • positive regulation of cell proliferation
  • regulation of G1/S transition of mitotic cell cycle
  • positive regulation of double-strand break repair
  • regulation of nucleotide-excision repair
  • regulation of G0 to G1 transition
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • SWI/SNF complex
  • chromatin

Gene-Specific Assays for Results You Can Trust

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