Mrpl17 Gene Summary [Mouse]

Predicted to enable protein domain specific binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochondrial inner membrane. Is expressed in several structures, including early conceptus; gonad; skeleton; submandibular gland primordium; and thymus primordium. Orthologous to human MRPL17 (mitochondrial ribosomal protein L17). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrpl17
Official Name
mitochondrial ribosomal protein L17 [Source:MGI Symbol;Acc:MGI:1351608]
Ensembl ID
ENSMUSG00000030879
Bio databases IDs NCBI: 27397 Ensembl: ENSMUSG00000030879
Aliases mitochondrial ribosomal protein L17
Synonyms bL17m, L17mt, LIP2, mitochondrial ribosomal protein L17, MRP-L26, RPL17L, RPML26, Sodium/calcium exchanger-associated
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ribosomal protein L17
  • structural constituent of ribosome
  • protein domain specific binding
  • protein binding

Pathways

Biological processes and signaling networks where the Mrpl17 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colorectal adenoma
  • colorectal adenoma formation
regulated by
regulates
  • mitochondrial DNA
role in cell
  • translation in
  • autophagy in
  • autophagy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl17 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • protein domain specific binding
  • protein binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

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