Zmym3 Gene Summary [Mouse]
Predicted to enable zinc ion binding activity. Predicted to be involved in cytoskeleton organization and regulation of cell morphogenesis. Predicted to be located in nucleoplasm. Is expressed in several structures, including genitourinary system; liver; lung; nervous system; and spleen. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human ZMYM3 (zinc finger MYM-type containing 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zmym3 |
| Official Name | zinc finger, MYM-type 3 [Source:MGI Symbol;Acc:MGI:1927231] |
| Ensembl ID | ENSMUSG00000031310 |
| Bio databases IDs | |
| Aliases | zinc finger, MYM-type 3 |
| Synonyms | 9030216B10Rik, DXS6673E, DXS6673El, MYM, XFIM, XLID112, Zfp261, zinc finger, MYM-type 3, zinc finger MYM-type containing 3, ZNF198L2, ZNF261 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zmym3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF3504)
- protein binding
- DNA binding
- Ribosomal_L24e_L24
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- medulloblastoma
- brain cancer
- X-linked intellectual developmental disorder type 112
role in cell
- cell death
- formation
- formation in
- organization
- morphogenesis
- homologous recombination in
- olaparib sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zmym3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoskeleton organization
- regulation of cell morphogenesis
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- zinc ion binding
- protein binding