Ctps2 Gene Summary [Mouse]
Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in CTP biosynthetic process and pyrimidine nucleobase biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human CTPS2 (CTP synthase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ctps2 |
| Official Name | cytidine 5'-triphosphate synthase 2 [Source:MGI Symbol;Acc:MGI:1933185] |
| Ensembl ID | ENSMUSG00000031360 |
| Bio databases IDs | |
| Aliases | cytidine 5'-triphosphate synthase 2 |
| Synonyms | A830031M15RIK, Ctpsh, CTP synthase 2, cytidine 5'-triphosphate synthase 2, GATD5B |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ctps2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CTP binding site
- Glutamine amidotransferase class-I
- CTP synthase N-terminus
- CTP synthase
- enzyme
- protein binding
- identical protein binding
- Type 1 glutamine amidotransferase (GATase1)-like domain
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ctps2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- CTP biosynthetic process
- 'de novo' CTP biosynthetic process
- glutamine metabolic process
- pyrimidine nucleotide metabolic process
- pyrimidine base biosynthetic process
Cellular Component
Where in the cell the gene product is active
- cytoophidium
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- identical protein binding
- protein binding
- CTP synthase activity