Taf1d Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in cytosol; microtubule cytoskeleton; and nucleolus. Predicted to be part of RNA polymerase transcription factor SL1 complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human TAF1D (TATA-box binding protein associated factor, RNA polymerase I subunit D). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Taf1d |
| Official Name | TATA-box binding protein associated factor, RNA polymerase I, D [Source:MGI Symbol;Acc:MGI:1922566] |
| Ensembl ID | ENSMUSG00000031939 |
| Bio databases IDs | |
| Aliases | TATA-box binding protein associated factor, RNA polymerase I, D |
| Synonyms | 2810003M17Rik, 4930553M18Rik, 5930426I11Rik, JOSD3, MGC5306, RAFI41, RGD1309627, TAFI41, TAF(I)41, TATA-box binding protein associated factor, RNA polymerase I, D, TATA-box binding protein associated factor, RNA polymerase I subunit D |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Taf1d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TATA box-binding protein-associated factor 1D
- protein binding
- identical protein binding
Pathways
Biological processes and signaling networks where the Taf1d gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- organismal death
- neoplasia
- breast cancer
role in cell
- expression in
- proliferation
- growth
- cell viability
- colony formation
- cell cycle progression
- G2/M phase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- centrosome
- cytosol
- nucleoplasm
- nucleoli
- mitotic spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Taf1d gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- RNA polymerase transcription factor SL1 complex
- mitotic spindle
- centriolar satellite
- cytosol
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- identical protein binding
- protein binding