Ppp1r18 Gene Summary [Mouse]
Predicted to enable actin binding activity and phosphatase binding activity. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in nervous system. Orthologous to human PPP1R18 (protein phosphatase 1 regulatory subunit 18). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppp1r18 |
| Official Name | protein phosphatase 1, regulatory subunit 18 [Source:MGI Symbol;Acc:MGI:1923698] |
| Ensembl ID | ENSMUSG00000034595 |
| Bio databases IDs | |
| Aliases | protein phosphatase 1, regulatory subunit 18 |
| Synonyms | 2310014H01Rik, FLJ43651, HKMT1098, KIAA1949, PPR18, protein phosphatase 1 regulatory subunit 18, protein phosphatase 1, regulatory subunit 18, RGD1309543 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp1r18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Phostensin PP1-binding and SH3-binding region
- PP1-regulatory protein, Phostensin N-terminal
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insomnia
- breast carcinoma
- chronic obstructive pulmonary disease
- lung carcinoma
- lung carcinoma process
role in cell
- expression in
- formation
- formation in
- number
- activity
- size
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- actin ring
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppp1r18 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- phosphatase binding
- protein binding
- actin binding