Galp Gene Summary [Mouse]
Predicted to enable signaling receptor binding activity. Acts upstream of or within behavioral response to starvation and regulation of appetite. Predicted to be located in extracellular region. Is expressed in several structures, including Harderian gland; alimentary system; genitourinary system; immune system; and liver and biliary system. Orthologous to human GALP (galanin like peptide). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Galp |
| Official Name | galanin-like peptide [Source:MGI Symbol;Acc:MGI:2663979] |
| Ensembl ID | ENSMUSG00000034660 |
| Bio databases IDs | |
| Aliases | galanin-like peptide |
| Synonyms | AF188491, GAL, galanin-like peptide |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Galp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- receptor binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- weight loss
- insomnia
- edema
- weight gain
- obesity
- anorexia
- hypoleptinemia
- diabetes mellitus
- microalbuminuria
- hyperthermia
role in cell
- quantity
- expression in
- activation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- axons
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Galp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- response to insulin stimulus
- regulation of appetite
- defense response to Gram-negative bacterium
- behavioral response to starvation
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- hormone activity