Galp Gene Summary [Rat]

Predicted to enable hormone activity. Involved in response to insulin. Predicted to be located in extracellular region. Biomarker of obesity. Orthologous to human GALP (galanin like peptide). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Galp
Official Name
galanin-like peptide [Source:RGD Symbol;Acc:620187]
Ensembl ID
ENSRNOG00000022129
Bio databases IDs NCBI: 64568 Ensembl: ENSRNOG00000022129
Aliases galanin-like peptide
Synonyms AF188491, GAL, galanin-like peptide
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Galp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • receptor binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • weight loss
  • insomnia
  • edema
  • weight gain
  • obesity
  • anorexia
  • hypoleptinemia
  • diabetes mellitus
  • microalbuminuria
  • hyperthermia
regulated by
  • lipopolysaccharide
  • LEP
  • polyunsaturated fatty acids
  • LEPR
  • SORL1
  • POMC
regulates
role in cell
  • quantity
  • expression in
  • activation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • axons
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Galp gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuropeptide signaling pathway
  • response to insulin stimulus
  • regulation of appetite
  • defense response to Gram-negative bacterium
  • behavioral response to starvation

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • hormone activity

Gene-Specific Assays for Results You Can Trust

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