Rrp9 Gene Summary [Mouse]

Predicted to enable U3 snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of box C/D methylation guide snoRNP complex and small-subunit processome. Is expressed in embryo and extraembryonic component. Orthologous to human RRP9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Rrp9
Official Name
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:MGI Symbol;Acc:MGI:2384313]
Ensembl ID
ENSMUSG00000041506
Bio databases IDs NCBI: 27966 Ensembl: ENSMUSG00000041506
Aliases ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
Synonyms D9Wsu10e, ribosomal RNA processing 9, U3 small nucleolar RNA binding protein, RNU3IP2, U3-55K
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rrp9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • WD40 repeats
  • WD domain, G-beta repeat
  • snoRNA binding
  • WD40
  • protein binding

Pathways

Biological processes and signaling networks where the Rrp9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colorectal cancer
  • keloid disease
regulated by
regulates
role in cell
  • growth
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • pre-ribosome
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rrp9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal small subunit biogenesis
  • rRNA processing

Cellular Component

Where in the cell the gene product is active
  • box C/D snoRNP complex
  • small-subunit processome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • snoRNA binding
  • protein binding
  • RNA binding
  • U3 snoRNA binding