Rpl37 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in positive regulation of signal transduction by p53 class mediator. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Orthologous to human RPL37 (ribosomal protein L37). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl37 |
| Official Name | ribosomal protein L37 [Source:MGI Symbol;Acc:MGI:1914531] |
| Ensembl ID | ENSMUSG00000041841 |
| Bio databases IDs | |
| Aliases | ribosomal protein L37 |
| Synonyms | 3110005M08Rik, eL37, L37, LOC100506548, ribosomal protein L37 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl37 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- enzyme inhibitor activity
- protein binding
- enzyme regulator activity
- Ribosomal protein L37e
- growth factor binding
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl37 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-small cell lung cancer
- inflammatory bowel disease
role in cell
- expression in
- apoptosis
- cell death
- ubiquitination in
- stabilization in
- autoubiquitination in
- translation in
- G2 phase
- necroptosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- cytosol
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl37 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- cytosolic ribosome
- cytoplasm
- cytosol
- cytosolic large ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- structural constituent of ribosome
- metal ion binding
- rRNA binding