Wipi1

Predicted to enable several functions, including nuclear receptor binding activity; phosphatidylinositol phosphate binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in several processes, including macroautophagy; positive regulation of autophagosome assembly; and vesicle targeting, trans-Golgi to endosome. Located in phagophore assembly site. Is expressed in several structures, including central nervous system and retina. Orthologous to human WIPI1 (WD repeat domain, phosphoinositide interacting 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wipi1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Wipi1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Wipi1 gene, providing context for its role in the cell.