Elmod1 Gene Summary [Mouse]

Predicted to enable GTPase activator activity. Acts upstream of or within cilium assembly and protein transport. Is active in Golgi apparatus; cilium; and glutamatergic synapse. Is expressed in several structures, including brain; genitourinary system; inner ear; skin; and spinal cord. Orthologous to human ELMOD1 (ELMO domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Elmod1
Official Name
ELMO/CED-12 domain containing 1 [Source:MGI Symbol;Acc:MGI:3583900]
Ensembl ID
ENSMUSG00000041986
Bio databases IDs NCBI: 270162 Ensembl: ENSMUSG00000041986
Aliases ELMO/CED-12 domain containing 1
Synonyms 4831417L10, AI428506, AI834991, ELMO/CED-12 domain containing 1, ELMO domain containing 1, LOC643923, RGD1564186
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Elmod1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ELMO/CED-12 family
  • GTPase activator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • albuminuria
  • sneeze
  • hearing loss
  • cleft palate
  • cerebral amyloid angiopathy
regulated by
role in cell
  • fusion
  • fusion in
  • degeneration in
  • degeneration
  • elongation in
  • elongation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • glutaminergic synapse
  • cilia
  • Golgi Apparatus
  • synapse

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Elmod1 gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • GTPase activator activity

Gene-Specific Assays for Results You Can Trust

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