Hspb3

Predicted to be located in nucleus. Predicted to be active in cytoplasm and nuclear speck. Is expressed in several structures, including limb segment; lung; nervous system; skeletal musculature; and submandibular gland. Human ortholog(s) of this gene implicated in autosomal dominant distal hereditary motor neuronopathy 4. Orthologous to human HSPB3 (heat shock protein family B (small) member 3). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hspb3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Hspb3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Hspb3 gene, providing context for its role in the cell.