Pcdhb2 Gene Summary [Mouse]
Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Is expressed in cerebral cortex. Orthologous to human PCDHB2 (protocadherin beta 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pcdhb2 |
| Official Name | protocadherin beta 2 [Source:MGI Symbol;Acc:MGI:2136735] |
| Ensembl ID | ENSMUSG00000051599 |
| Bio databases IDs | |
| Aliases | protocadherin beta 2 |
| Synonyms | PcdhbB, PCDH-BETA2, PROTOCADHERIN beta2, protocadherin β 2, RGD1563132 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcdhb2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin-like
- Cadherin repeat-like domain
- Cadherin cytoplasmic C-terminal
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcdhb2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- synapse assembly
- calcium-dependent cell-cell adhesion
- nervous system development
- synaptic transmission
- cell adhesion
- homophilic cell adhesion
Cellular Component
Where in the cell the gene product is active
- membrane
- synapse
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding