Glipr1 Gene Summary [Mouse]
Predicted to be involved in sexual reproduction. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. Orthologous to human GLIPR1 (GLI pathogenesis related 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Glipr1 |
| Official Name | GLI pathogenesis-related 1 (glioma) [Source:MGI Symbol;Acc:MGI:1920940] |
| Ensembl ID | ENSMUSG00000056888 |
| Bio databases IDs | |
| Aliases | GLI pathogenesis-related 1 (glioma) |
| Synonyms | 2410114O14Rik, CRISP7, GLIOMA PATHOGENESIS RELATED, GLI pathogenesis-related 1, GLIPR, LOC120093588, mRTVP-1, RTVP-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Glipr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains
- CAP
- signal peptide
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- glioblastoma
- glioblastoma cancer
- endometrial cancer
- prostate cancer
- androgenic alopecia
- laser induced choroidal neovascularization
- prostatic intraepithelial neoplasia
role in cell
- expression in
- proliferation
- apoptosis
- phosphorylation in
- binding in
- cell cycle progression
- degradation in
- transactivation in
- destruction in
- ubiquitination in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- detergent resistant lipid raft fraction
- Plasma Membrane
- secretory granule membrane
- lysosome membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Glipr1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- membrane
- azurophil granule membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding