Senp7 Gene Summary [Rat]
Predicted to enable SUMO-specific endopeptidase activity. Predicted to be involved in antiviral innate immune response and protein desumoylation. Predicted to be active in nucleus; postsynaptic cytosol; and presynaptic cytosol. Orthologous to human SENP7 (SUMO specific peptidase 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Senp7 |
| Official Name | SUMO specific peptidase 7 [Source:RGD Symbol;Acc:1305510] |
| Ensembl ID | ENSRNOG00000001616 |
| Bio databases IDs | |
| Aliases | SUMO specific peptidase 7 |
| Synonyms | 2410152H17Rik, 2810413I22RIK, 2900036C23RIK, 6030449K19Rik, SSP2, SUMO1/sentrin specific peptidase 7, SUMO specific peptidase 7, SUSP2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Senp7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cysteine endopeptidase
- catalytic domain
- Ulp1 protease family, C-terminal catalytic domain
- peptidase
- protein binding
- ubiquitin-like-specific protease
Pathways
Biological processes and signaling networks where the Senp7 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- myeloproliferative disorder
- COVID-19
- breast cancer
- dermatological disorder
- actinic keratosis
role in cell
- expression in
- proliferation
- degradation in
- production in
- size
- number
- quantity
- oxidative phosphorylation in
- glycolysis in
- sumoylation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Senp7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein desumoylation
- proteolysis
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- SUMO-specific endopeptidase activity