Gnb1l Gene Summary [Rat]
Predicted to be involved in DNA damage checkpoint signaling. Predicted to act upstream of or within social behavior. Predicted to be located in cytoplasm and nucleus. Orthologous to human GNB1L (G protein subunit beta 1 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gnb1l |
| Official Name | G protein subunit beta 1 like [Source:RGD Symbol;Acc:1594165] |
| Ensembl ID | ENSRNOG00000001891 |
| Bio databases IDs | |
| Aliases | G protein subunit beta 1 like |
| Synonyms | DGCRK3, ESTM55, FKSG1, G beta L, Gm16314, G protein subunit beta 1 like, G protein subunit β 1 like, guanine nucleotide binding protein (G protein), beta polypeptide 1-like, guanine nucleotide binding protein (G protein), β polypeptide 1-like, GY2, G β L, LOC682392, Me49f07, Rtl10, WDR14, WDVCF |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gnb1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Anaphase-promoting complex subunit 4 WD40 domain
- WD40 repeats
- WD domain, G-beta repeat
- WD40
Pathways
Biological processes and signaling networks where the Gnb1l gene in rat plays a role, providing insight into its function and relevance in health or disease.
- AMPK Signaling
- Antiproliferative Role of Somatostatin Receptor 2
- Apelin Endothelial Signaling Pathway
- Apelin Muscle Signaling Pathway
- Autophagy
- CCR3 Signaling in Eosinophils
- CXCR4 Signaling
- Docosahexaenoic Acid (DHA) Signaling
- Endocannabinoid Cancer Inhibition Pathway
- Endocannabinoid Developing Neuron Pathway
- Ephrin B Signaling
- Ephrin Receptor Signaling
- fMLP Signaling in Neutrophils
- Glutamate Receptor Signaling
- Gαq Signaling
- Gαs Signaling
- HER-2 Signaling in Breast Cancer
- IL-1 Signaling
- Molecular Mechanisms of Cancer
- P2Y Purinergic Receptor Signaling Pathway
- Polyamine Regulation in Colon Cancer
- Protein Kinase A Signaling
- RhoGDI Signaling
- SAPK/JNK Signaling
- Thrombin Signaling
- α-Adrenergic Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Gnb1l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA damage checkpoint
- response to DNA damage stimulus
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm