Rbm3 Gene Summary [Rat]
Predicted to enable RNA binding activity and ribosomal large subunit binding activity. Involved in positive regulation of translation. Located in cytoplasm; dendrite; and nucleus. Part of large ribosomal subunit. Orthologous to human RBM3 (RNA binding motif protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rbm3 |
| Official Name | RNA binding motif protein 3 [Source:RGD Symbol;Acc:620145] |
| Ensembl ID | ENSRNOG00000005387 |
| Bio databases IDs | |
| Aliases | RNA binding motif protein 3 |
| Synonyms | 2600016C11Rik, IS1-RNPL, RNA binding motif protein 3, RNA binding motif (RNP1, RRM) protein 3, RNPL |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rbm3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- protein binding
- ribosomal large subunit binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- liver cancer
- hepatocellular carcinoma
- prostate cancer
- epithelial cancer
- androgenic alopecia
- organismal death
- behavioral deficit
- hepatitis A
- spongiosis
role in cell
- apoptosis
- proliferation
- degradation in
- phosphorylation in
- migration
- expression in
- translation in
- growth
- cell cycle progression
- loss
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- ribosome
- nucleoplasm
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rbm3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translation
- positive regulation of translation
- positive regulation of nuclear mRNA splicing, via spliceosome
- RNA processing
Cellular Component
Where in the cell the gene product is active
- dendrite
- nucleus
- cytoplasm
- spliceosomal complex
- large ribosomal subunit
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- ribosomal large subunit binding