Podxl2 Gene Summary [Rat]
Predicted to be involved in leukocyte tethering or rolling. Predicted to be located in plasma membrane. Orthologous to human PODXL2 (podocalyxin like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Podxl2 |
| Official Name | podocalyxin-like 2 [Source:RGD Symbol;Acc:1305815] |
| Ensembl ID | ENSRNOG00000016255 |
| Bio databases IDs | |
| Aliases | podocalyxin-like 2 |
| Synonyms | D130074J02Rik, EG, PODLX2, podocalyxin-like 2, RGD1305815 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Podxl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CD34/Podocalyxin family
- protein binding
- glycosaminoglycan binding
Pathways
Biological processes and signaling networks where the Podxl2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Golgi lumen
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Podxl2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- leukocyte tethering or rolling
Cellular Component
Where in the cell the gene product is active
- Golgi lumen
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- glycosaminoglycan binding