LOC100911456 Gene Summary [Rat]
Predicted to be involved in negative regulation of G2/M transition of mitotic cell cycle and negative regulation of cell migration. Orthologous to human MIIP (migration and invasion inhibitory protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | LOC100911456 |
| Official Name | migration and invasion-inhibitory protein-like [Source:RGD Symbol;Acc:6492682] |
| Ensembl ID | ENSRNOG00000024139 |
| Bio databases IDs | |
| Aliases | migration and invasion-inhibitory protein-like |
| Synonyms | D4Wsu114e, IIP45, LOC100911456, migration and invasion inhibitory protein |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc100911456 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Migration and invasion-inhibitory
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- metastasis
- colorectal cancer
- atopic dermatitis
- glioma formation
- overall survival
role in cell
- expression in
- activation in
- growth
- phosphorylation in
- epithelial-mesenchymal transition
- migration
- binding in
- colony formation
- interaction in
- acetylation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Loc100911456 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of G2/M transition of mitotic cell cycle
- negative regulation of cell migration
Molecular Function
What the gene product does at the molecular level
- protein binding